1 Enter claim
2 Add references
3 Review verdict
4 Download highlighted PDF
5 Check ABPI compliance
Step 1 — Enter claim
Paste a single claim, a paragraph, or a manuscript section (up to ~50 claims).
Step 2 — Upload references or select from Library
Drag & drop or click to browse
local_library Library
Loading library...
0 selected
Step 3 — Verify
Runs verification against the selected references.
Comprehensive verification aid. Always apply professional editorial judgement. Cross-reference findings independently before submission.
1 Describe claim
2 Choose sources
3 Review results
Search across
1 source selected
Generating search strategy…

Results

upload_file

Drop PDF references here or click to browse

Upload your reference PDFs to build your library. Max 20 files at a time.

Medical writers often spend hours checking whether claims are supported by their cited references — searching PDFs, matching endpoints and statistics, and flagging anything that doesn't align.

RefCheckr automates the most time-consuming parts of that process. Paste a claim, upload the references, and RefCheckr locates the exact supporting passage and returns a clear verdict in seconds.

Without RefCheckr
  • remove Search PDFs manually
  • remove Skim pages for endpoints and numbers
  • remove Confirm wording matches the source
  • remove Leave "unable to verify" comments
With RefCheckr
  • check Paste the claim
  • check Upload references or select from your library
  • check RefCheckr highlights the supporting passage
  • check Get a verdict in seconds

Verify a Claim

Check whether a specific claim is supported by its cited reference.

1 edit_note
Paste your claim(s)
Enter a single claim, paste a paragraph, or drop in an entire manuscript section. RefCheckr extracts the verifiable claims and detects citation markers so each claim can be checked against the reference it actually cites.
2 upload_file
Add your references
Upload up to 10 source PDFs (20 for Pro), or select references from your library. RefCheckr parses each document's structure — pages, columns, paragraphs, and line numbers — and checks your claim against every reference.
3 verified
Get your verdict
RefCheckr locates the exact supporting passage, highlights it in context, and delivers a verdict: Strong Support, Partial Support, Implied by Data, Not Supported, Contradicted, or Overclaim.

In batch mode, each claim gets its own colour-coded verdict so you can quickly scan for supported statements and focus on the ones that need attention. Pro users can also listen to an audio brief of the results.

Check ABPI Compliance

Assess whether your claim meets the ABPI Code of Practice.

1 verified
Run a compliance check
After reviewing your verification verdict, click "Check ABPI compliance" to assess the claim against the 2024 ABPI Code of Practice.
2 policy
Review the risk rating
RefCheckr returns a risk rating — Low risk, Review recommended, or High risk — along with a rationale and the relevant ABPI clauses retrieved from the code of practice.
3 edit_note
Apply the suggested rewrite or ask a question
For claims rated as borderline or high risk, RefCheckr suggests a rewrite. You can also ask follow-up questions about ABPI clauses directly in the built-in compliance chat.

You can also check ABPI compliance before verification in Step 1 — useful for fixing wording before spending a verification. Powered by MedCheckr with RAG-backed clause retrieval from the ABPI Code of Practice.

An annotated PDF exported by RefCheckr, with supporting passages highlighted in context

An annotated PDF export with supporting passages highlighted in context.

Find References

Search multiple databases for references that might support a claim.

1
Enter a clinical claim
Describe the claim you need to find supporting evidence for. RefCheckr generates an optimised search strategy automatically.
2
Choose your sources
Search across PubMed (literature), ClinicalTrials.gov (trial registrations), DailyMed/OpenFDA (US prescribing information), and eMC (UK SmPC). Toggle sources on or off.
3
Review ranked results
Results are grouped by source and ranked by relevance. Each PubMed article includes a brief assessment of how it relates to your claim.

What powers RefCheckr

Built on established biomedical infrastructure, not just a language model wrapper.

Analysis
Perplexity AI (Sonar) for claim verification and relevance assessment
Literature
PubMed / NCBI via PubCrawl MCP server
Trials
ClinicalTrials.gov API via PubCrawl
Labelling
DailyMed (FDA structured product labels) and OpenFDA via PubCrawl
Compliance
MedCheckr API — OpenAI GPT-4o-mini for assessment, with RAG-backed clause retrieval from the 2024 ABPI Code of Practice
PDF parsing
Page, column, paragraph and line-level extraction with structural markers
Visual analysis
Claude Sonnet 4 (Pro) for interpreting tables, figures, Kaplan-Meier curves, and forest plots

Frequently asked questions

Common questions about RefCheckr.

Is RefCheckr free?
You can sign up for free and get 10 verifications and 10 reference searches to try RefCheckr. The Pro plan gives you unlimited usage, table & figure analysis, audio briefs, and priority support.
How do I cancel my subscription?
You can cancel anytime from the Settings page — just click "Manage subscription" under your plan details. Cancellation takes effect at the end of your current billing period, so you keep access until then. No questions asked.
What file formats are supported?
PDF and plain text. PDFs are parsed with full structural awareness — pages, columns, paragraphs, and line numbers — so RefCheckr can pinpoint exactly where a supporting passage lives.
Which AI model does RefCheckr use?
Perplexity AI (Sonar) for text-based claim analysis and relevance assessment. Claude Sonnet 4 (Pro only) for visual analysis of tables and figures. OpenAI GPT-4o-mini for ABPI compliance assessment, with RAG-backed clause retrieval. Literature search, clinical trials, and drug labelling are handled by PubCrawl, which queries PubMed, ClinicalTrials.gov, and DailyMed directly — no LLM in the loop for those lookups.
Does RefCheckr store my documents?
Ad-hoc uploads are processed in memory and discarded after verification. If you save a reference to your library, RefCheckr stores the extracted text and a copy of the PDF so you can verify against it again without re-uploading. You can delete any library reference at any time.
How accurate is the verification?
RefCheckr is designed to catch overclaims, unsupported statistics, and mismatched data — the kinds of errors that slip through manual checking. But it's a verification aid, not an infallible oracle. Always apply professional editorial judgement, especially for regulatory submissions.
What is the Reference Library?
The Reference Library lets you upload your reference PDFs once and verify claims against them repeatedly — no need to re-upload the same files each time. This is especially useful when you're checking many claims against a fixed set of references for a manuscript. Free users can store up to 10 references; Pro users get up to 200. You can also save references directly from your verification results using the "Save to Library" button.
Can I verify multiple claims at once?
Yes. Paste a paragraph or manuscript section into the claim field — RefCheckr will detect multiple sentences and offer to split them into individual claims automatically. Each claim gets its own verdict against your uploaded references, and you'll see a summary showing how many are supported.
What is the ABPI compliance check?
After verifying a claim, you can check whether it meets the ABPI Code of Practice. RefCheckr retrieves the relevant clauses from the 2024 code and returns a risk rating (Low risk, Review recommended, or High risk) with a rationale. For borderline or high-risk claims, it suggests a compliant rewrite. You can also ask follow-up questions about the clauses using the built-in compliance chat, or check compliance before verification in Step 1.
Is the compliance check a substitute for PMCPA review?
No. The compliance check provides AI-generated interpretations based on the 2024 ABPI Code of Practice. It is intended as decision-support only and does not represent the views of the PMCPA. Always ensure your materials align with the latest published guidance and your company's internal review process.
Can I paste an entire manuscript section?
Yes. Paste your introduction, results, or discussion — RefCheckr extracts the verifiable claims, detects citation markers (e.g. [1,2] or superscript numbers), and lets you map each citation to an uploaded reference. Each claim is then checked against the specific reference it cites, with results shown in original order and colour-coded for quick scanning.
Can RefCheckr read tables and figures?
Yes — Pro users can enable "Analyse tables & figures" before verifying. RefCheckr automatically detects pages with tables or figures, renders them as images, and uses Claude Sonnet 4 to extract and verify data such as hazard ratios, p-values, and Kaplan-Meier curves. Visual evidence is shown alongside text-based passages in the results.
Can I use RefCheckr for regulatory submissions?
RefCheckr supports your reference-checking workflow but is not a validated regulatory tool. Use it for first-pass verification and to flag potential issues — then confirm critical claims manually before submission.
Verification aid, not a replacement for professional judgement. RefCheckr highlights supporting passages and flags potential issues, but professional editorial judgement should always be applied.

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Learn how RefCheckr handles claims and reference PDFs.

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RefCheckr v1.6.0

Get in touch

RefCheckr is developed by Nick Lamb at PharmaTools.AI. Get in touch for bug reports, feature requests, or enterprise access enquiries.

We aim to respond within 1–2 business days.

Found a bug or unexpected result? If possible, include the claim and reference used so we can investigate.

Enterprise & Partnerships

Interested in using RefCheckr across your team or organisation? We're happy to discuss team access, workflow integration, API access, or enterprise licensing.

Contact nick@pharmatools.ai to start the conversation.

12 April 2026
v1.6.0

Scientific Integrity Report

  • New report after batch verification — every batch analysis now generates a shareable Scientific Integrity Report with a stable URL. Open it from the results panel or the History page.
  • MLR-ready format — reports are structured for medical review, with an overall assessment, high-risk claims, and cited evidence passages.
  • Reviewer Summary — a concise overview at the top highlights key findings and recommended actions.
  • Print-ready reports — A4-friendly layout that can be saved as a PDF directly from the browser.
12 April 2026
v1.5.1

Smarter endpoint mismatch detection

  • Distinguishes strong and broad mismatches — "improves overall survival" against a PFS paper now reads as a different warning than "improves survival", with clearer messaging for each.
12 April 2026
v1.5.0

Spot claim–evidence mismatches

  • Potential mismatch warnings — RefCheckr now flags when your claim wording may go beyond what the cited evidence actually supports, such as mentioning overall survival when the evidence reports progression-free survival.
  • Four checks covered — endpoint mismatches, significance wording without supporting statistics, safety claims against efficacy-only evidence, and broad wording when a narrower endpoint is reported.
  • Advisory only — these warnings help you catch drift before it becomes a compliance issue. They do not affect the verification verdict.
11 April 2026
v1.4.0

Extracted findings

  • Structured evidence — after verifying a claim, RefCheckr now extracts key facts from the cited passages: study name, endpoint, hazard ratio, p-value, and more. Look for the "Extracted findings" section below your passages.
  • Endpoint normalization — common abbreviations like OS, PFS, and ORR are automatically mapped to their full names, so results are consistent and easy to scan.
  • Key result at a glance — the main numeric result (e.g., Hazard ratio: 0.80) is shown prominently at the top of the section so you can spot it immediately.
27 March 2026
v1.3.0

Drop in a manuscript section and ref pack

  • Paste an entire section — drop in your introduction, results, or discussion along with your ref pack. RefCheckr extracts the verifiable claims, detects the citation markers, and checks each claim against the reference it actually cites.
  • Colour-coded fact check — see your claims in original order, each marked green, amber, or red. Quickly confirm the supported statements and focus your time on the ones that need attention.
  • Citation mapping — RefCheckr detects citation numbers from your text and lets you assign them to your uploaded references. Click "Auto-assign by order" if your refs are uploaded in citation order.
  • Up to 20 references (Pro) — Pro users can now verify against up to 20 reference documents, enough to cover a full manuscript section.
22 March 2026
v1.2.0

Table & figure analysis

  • Analyse tables & figures — Pro users can now verify claims against data in tables, charts, and figures, not just text. Enable the "Analyse tables & figures" checkbox before verifying to have AI examine visual data in your references.
  • Visual evidence — results now show which tables or figures were analysed, what data was found, and specific values like hazard ratios, p-values, and confidence intervals.
  • Smart page detection — RefCheckr automatically identifies which PDF pages contain tables or figures, so only relevant pages are analysed.
22 March 2026
v1.1.0

Ask about ABPI compliance

  • Compliance chat — after checking ABPI compliance, ask follow-up questions about your claim directly in RefCheckr. Powered by MedCheckr, the chat understands your claim, verdict, and relevant clauses so you get contextual answers.
  • Suggested follow-ups — clickable follow-up questions appear after each response, making it easy to explore clauses, get rewording suggestions, or understand why a claim was flagged.
  • Pre-verification compliance check — check ABPI compliance in Step 1 before using a verification. Fix your wording first, then verify against your references.
  • Use suggested rewrite — when the compliance check suggests a rewrite, click "Use this claim" to swap it into the claim field instantly.
20 March 2026
v1.0.0

ABPI compliance check

  • Check ABPI compliance — after verifying a claim, click "Check ABPI compliance" to assess whether your claim meets the ABPI Code of Practice. Powered by MedCheckr with RAG-backed clause retrieval.
  • Relevant clauses — see the actual ABPI clause text retrieved from the code of practice, so you know exactly which rules apply and why.
  • Suggested rewrite — for borderline or non-compliant claims, get a suggested rewrite that addresses the compliance issues.
17 March 2026
v0.9.0

Reference Library

  • Upload once, verify many — upload your reference PDFs to a persistent library and verify claims against them without re-uploading. Perfect for manuscripts with a fixed set of references.
  • Library management — add, remove, rename, and search your stored references from the new Library page.
  • Verify from Library — on the Verify page, toggle between uploading PDFs and selecting from your library. You can mix both in a single verification.
  • Save to Library — after a verification, click "Save to Library" on any result to add that reference for future use without re-processing.
  • Duplicate detection — uploading the same PDF twice is automatically caught and skipped.
  • Usage limits — free plan: 10 library references, Pro: 200. Upgrade prompts appear as you approach the limit.
16 March 2026
v0.8.5

Stricter verification & new verdict

  • Anti-hallucination safeguards — RefCheckr now enforces that all supporting quotes are verbatim from your uploaded document. Fabricated or paraphrased quotes are automatically caught and downgraded.
  • New "Implied by Data" verdict — when a claim is supported by tables or figures but not explicitly stated in the text, RefCheckr now flags this clearly instead of marking it as strong support.
  • Highlight validation — if a quoted passage cannot be matched against the actual PDF text, the verdict is automatically downgraded. This prevents misleading results when the AI is confident but the evidence isn't there.
  • Clearer result wording — updated verdict descriptions to distinguish between explicit textual support and indirect data-based evidence.
14 March 2026
v0.8.4

Citation formatter

  • One-click citation copy — after searching for references, click "Cite" on any PubMed result to copy a formatted citation in Vancouver, APA, or Harvard style.
13 March 2026
v0.8.3

Share, export & feedback

  • Shareable verification links — click the share icon on any history item to generate a read-only link you can send to colleagues or clients. No account needed to view. Links expire after 30 days.
  • Export history as CSV — download your verification records as a spreadsheet from the History page. Handy for handing over to clients or keeping offline records.
  • Verdict feedback — thumbs up or down on every result, with an optional comment box to tell us what was helpful or what could be better.
13 March 2026
v0.8.2

Yearly plan & updated pricing

  • New yearly plan — get RefCheckr Pro for £9/month billed annually (£108/year), saving 69% compared to the monthly plan.
10 March 2026
v0.8.1

More references, better onboarding

  • Upload up to 10 PDFs — doubled the reference limit so you can verify claims against more sources at once.
  • Redesigned workflow steps — the Verify page now shows a cleaner, chip-style guide to help you get started.
  • History by project — verifications are now grouped by project with collapsible sections, hover actions, and a project filter.
  • Cancellation FAQ — added a clear answer on how to cancel your subscription.
9 March 2026
v0.8.0

Projects & usage stats

  • Projects — organise your verifications by document or deliverable. Pick a project from the dropdown on the Verify page, or create a new one inline.
  • Usage stats in Settings — see how many verifications and searches you've used at a glance, with clear progress bars and plan limits.
8 March 2026
v0.7.0

Dark mode

  • Full dark theme — easier on the eyes for late-night lit reviews. Toggle between System, Light, and Dark in Settings.
7 March 2026
v0.6.1

Paste a paragraph, get individual claims

  • Paragraph splitter — paste a full manuscript paragraph and we'll automatically break it into separate claims ready to verify
6 March 2026
v0.6.0

Batch claims

  • Verify up to 50 claims at once — paste or type multiple claims and check them all against your references in one go
  • Faster batch processing — claims are now verified together per document, cutting wait times significantly
5 March 2026
v0.5.0

Multi-PDF verification & Audio Briefs

  • Up to 10 PDFs (20 for Pro) — check claims against up to ten reference documents at once, or twenty with Pro
  • Audio Briefs — listen to a spoken summary of the verdict with one click (Pro)
4 March 2026
v0.4.0

Security, reliability & accessibility

  • Security hardening — admin endpoints now require authentication, SQL injection risks patched, CORS restricted to allowed origins, webhook signature verification strengthened, and security headers added across the board
  • PostgreSQL migration — replaced the in-memory SQLite database with PostgreSQL for better performance, reliability, and scalability
  • Structured logging — added Pino logging with request IDs for easier debugging and monitoring
  • Codebase modularisation — split the single-file backend into organised modules with dedicated routes, middleware, and services
  • Test suite & CI — added 32 automated tests and a GitHub Actions pipeline that runs on every push
  • Accessibility — full keyboard navigation, screen reader support with live announcements, focus management across pages and modals, and a skip-to-content link
3 March 2026
v0.3.0

OCR for scanned PDFs

  • OCR support — scanned and image-based PDFs are now automatically detected and processed, so you can verify claims against any PDF
  • History filters — filter past verifications by verdict type and date range
2 March 2026
v0.2.0

Highlighted PDF export

  • Download highlighted PDFs — get your reference back with supporting passages highlighted and colour-coded by verdict
  • Quick Start guides — visual step-by-step onboarding for both tools
28 February 2026
v0.1.0

Launch

  • Verify a Claim — upload a PDF, enter a claim, get a verdict with supporting passages
  • Find References — search PubMed, ClinicalTrials.gov, and drug labelling databases
  • Overclaim detection — flags where claims overstate what the reference actually says